Author

C. Jobin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

R. C. Newsome· 2 shared A. Byju· 1 shared A. De· 1 shared A. M. Peiper· 1 shared A. M. Rothemich· 1 shared A. N. Zuniga· 1 shared A. Riva· 1 shared A. Rogala· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

R. C. Newsome

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metabolic immaturity of newborns and breast milk bile acids are the central determinants of heightened neonatal vulnerability to norovirus diarrhea

A. M. Peiper, J. Morales, L. Phophi, Z. Hu, M. Phillips, C. G. Williams, S. Subramanian, M. Cross, N. Iyer, Q. Nguyen, R. C. Newsome, C. Jobin, S. N. Langel, S. Becker-Dreps, X.-D. Tan, , S. M. Karst

This study identifies metabolic immaturity in newborns and maternal bile acids in breast milk as key factors increasing vulnerability to norovirus diarrhea.

bioRxiv · May 1, 2024Microbiology

Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

Y. Feng, R. C. Newsome, T. Robinson, R. L. Bowman, A. N. Zuniga, K. N. Hall, C. M. Berntsen, D. E. Shabashvili, K. I. Krajcik, C. Gunaratne, Z. J. Zaroogian, K. Venugopal, H. L. Casellas Roman, R. L. Levine, W. K. Chatila, , O. A. Guryanova

This study shows that hematopoietic Dnmt3a haploinsufficiency worsens colitis-associated colon cancer by promoting angiogenesis, which can be targeted with axitinib.

bioRxiv · Dec 30, 2022 · PreprintCancer Biology

Bacterial Swarmers exhibit a Protective Response to Intestinal Stress

W. Chen, A. De, H. Li, J. R. Wright, R. Lamendella, D. J. Lukin, W. Szymczak, K. Sun, L. Kelly, S. Ghosh, D. B. Kearns, Z. He, C. Jobin, X. Luo, A. Byju, , S. Mani

This study identifies bacterial swarmers as protective against intestinal inflammation in mice and humans, showing their ability to enrich beneficial gut microbes.

bioRxiv · Oct 7, 2020 · PreprintMicrobiology

Microbiota Accelerates Age-Related CpG island Methylation in Colonic Mucosa

A. Sun, L. Cole, S. Maegawa, P. H. Park, K. Keith, J. Madzo, J. Jelinek, C. Jobin, J.-P. J. Issa

The paper shows microbiota accelerates age-related CpG island methylation in colonic mucosa, similar to cancer, and interacts with inflammation to enhance methylation changes.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology

Yersiniabactin producing AIEC promote inflammation-associated fibrosis in gnotobiotic Il10-/- mice

M. Ellermann, R. Gharaibeh, L. Fulbright, B. Dogan, L. N. Moore, C. A. Broberg, L. R. Lopez, A. M. Rothemich, J. Herzog, A. Rogala, I. O. Gordon, F. Rieder, C. R. Brouwer, K. W. Simpson, C. Jobin, , J. C. Arthur

The paper shows that Yersiniabactin-producing AIEC bacteria cause inflammation-associated fibrosis in mice, with Ybt import receptor FyuA influencing fibrosis severity.

bioRxiv · Aug 2, 2019Microbiology