Author

I. Pustova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:Hi-C· 1 Organism:mouse· 1

Frequent Co-Authors

A. S. Hansen· 3 shared C. Cattoglio· 3 shared R. Tjian· 3 shared X. Darzacq· 3 shared C. J. Inouye· 1 shared G. M. Dailey· 1 shared J. Ellenberg· 1 shared J. J. Ho· 1 shared

Activity by Year

2016-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

A. S. Hansen

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3 papers

Recent·Most cited

Determining cellular CTCF and cohesin abundances to constrain 3D genome models

C. Cattoglio, I. Pustova, N. Walther, J. J. Ho, M. Hantsche-Grininger, C. J. Inouye, M. J. Hossain, G. M. Dailey, J. Ellenberg, X. Darzacq, R. Tjian, A. S. Hansen

The paper quantifies CTCF and cohesin levels in mammalian cells to improve 3D genome models and provides a method for measuring Halo-tagged proteins.

bioRxiv · Feb 24, 2019Biophysics

An RNA-binding region regulates CTCF clustering and chromatin looping

A. S. Hansen, T.-H. S. Hsieh, C. Cattoglio, I. Pustova, X. Darzacq, R. Tjian

The paper shows that an RNA-binding region in CTCF mediates chromatin looping and clustering, revealing two classes of CTCF loops: RBR-dependent and RBR-independent.

bioRxiv · Dec 16, 2018Biophysics

CTCF and Cohesin Regulate Chromatin Loop Stability with Distinct Dynamics

A. S. Hansen, I. Pustova, C. Cattoglio, R. Tjian, X. Darzacq

This study shows CTCF and cohesin form a dynamic complex with distinct binding dynamics, suggesting chromatin loops constantly break and reform.

bioRxiv · Dec 13, 2016Biophysics