Author

J. J. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2

Frequent Co-Authors

X. Darzacq· 3 shared A. Sule· 2 shared B. Margolin· 2 shared C. Inouye· 2 shared D. J. Anderson· 2 shared D. T. McSwiggen· 2 shared E. Gonzalez· 2 shared E.-B. Choi· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiophysics

X. Darzacq

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Oblique Line Scan Illumination Enables Expansive, Accurate and Sensitive Single Protein Measurements in Solution and in Living Cells

A. Driouchi, M. Bretan, B. J. Davis, A. B. Heckert, M. Seeger, M. Bradley Silva, W. S. Forrest, J. Hsiung, J. Tan, H. Yang, D. T. McSwiggen, L. Song, A. Sule, B. Abaie, B. Conroy, , D. J. Anderson

This paper introduces Oblique Line Scan (OLS) illumination to enhance single-molecule tracking in living cells and solution, enabling high-throughput and sensitive protein dynamics measurements.

bioRxiv · Dec 21, 2023Biophysics

A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

D. T. McSwiggen, H. Liu, R. Tan, S. Agramunt Puig, L. B. Akella, R. Berman, M. Bretan, H. Chen, X. Darzacq, K. Ford, R. Godbey, E. Gonzalez, A. Hanuka, A. Heckert, J. J. Ho, , H. Beck

This paper introduces a high-throughput single-molecule tracking platform to study protein dynamics and drug interactions, identifying novel mechanisms and therapeutics.

bioRxiv · Jan 5, 2023Cell Biology

SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating Hes5

E.-B. Choi, M. Vodnala, P. Saini, M. Zerbato, J. J. Ho, S. Anugula, J. Wang, S. H. Sui, J. Yoon, C. Inouye, Y. W. Fong

This study identifies SOX15's role in maintaining pluripotency and promoting neural differentiation by interacting with coactivators and activating Hes5.

bioRxiv · Apr 25, 2022 · PreprintCell Biology

ATP-binding cassette protein ABCF1 couples gene transcription with maintenance of genome integrity in embryonic stem cells

E.-B. Choi, M. Vodnala, M. Zerbato, J. Wang, J. J. Ho, C. Inouye, Y. W. Fong

This study identifies ABCF1 as a coactivator for OCT4/SOX2 that links transcription with DNA damage sensing to maintain stem cell pluripotency and genome integrity.

bioRxiv · May 28, 2020 · PreprintBiochemistry

Determining cellular CTCF and cohesin abundances to constrain 3D genome models

C. Cattoglio, I. Pustova, N. Walther, J. J. Ho, M. Hantsche-Grininger, C. J. Inouye, M. J. Hossain, G. M. Dailey, J. Ellenberg, X. Darzacq, R. Tjian, A. S. Hansen

The paper quantifies CTCF and cohesin levels in mammalian cells to improve 3D genome models and provides a method for measuring Halo-tagged proteins.

bioRxiv · Feb 24, 2019Biophysics