Author

I. Riven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 7

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 5 Assay:fluorescence / live-cell microscopy· 3 Approach:microscopy & imaging analysis· 2 Organism:E. coli· 1 Assay:protein structure· 1

Frequent Co-Authors

G. Haran· 7 shared D. Levy· 4 shared M. Iljina· 4 shared D. Scheerer· 2 shared H. Mazal· 2 shared R. Naaman· 2 shared S. Ghosh· 2 shared A. Dayananda· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersBiophysics

G. Haran

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

From Microstates to Macrostates in the Conformational Dynamics of GroEL: a Single-Molecule FRET Study

D. G. Liebermann, J. Jungwirth, I. Riven, Y. Barak, D. Levy, A. Horovitz, G. Haran

This study uses single-molecule FRET to analyze conformational dynamics of GroEL subunits, revealing four microstates and their macrostate transitions under different solution conditions.

bioRxiv · Mar 23, 2023Biophysics

Single-molecule FRET probes allosteric effects on protein-translocating pore loops of a AAA+ machine

M. Iljina, H. Mazal, A. Dayananda, Z. Zhang, G. Stan, I. Riven, G. Haran

This study uses single-molecule FRET to show that ATP hydrolysis in ClpB's nucleotide binding domains allosterically controls pore loop dynamics, revealing long-range conformational changes essential for substrate translocation.

bioRxiv · Feb 2, 2023Biophysics

Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase

D. Scheerer, B. V. Adkar, S. Bhattacharyya, D. Levy, M. Iljina, I. Riven, O. Dym, G. Haran, E. Shakhnovich

This study investigates how AMP substrate inhibition in adenylate kinase is modulated by domain motions, showing that inhibitory concentrations of AMP increase domain closure and affect catalytic activity.

bioRxiv · Nov 21, 2022 · PreprintBiophysics

Control of protein activity by photoinduced spin polarized charge reorganization

S. Ghosh, K. B. Ghosh, D. Levy, D. Scheerer, I. Riven, J. Shin, H. Gray, R. Naaman, G. Haran

This study demonstrates that photoinduced spin polarized charge reorganization within proteins can modulate enzyme activity and protein-protein interactions.

bioRxiv · Oct 12, 2021Biophysics

Substrates modulate charge-reorganization allosteric effects in protein-protein association

K. Banerjee-Ghosh, S. Ghosh, D. Levy, I. Riven, R. Naaman, G. Haran

The paper investigates how charged substrates modulate charge-reorganization allosteric effects in protein-protein association, showing that ATP reduces this effect by over 50%.

bioRxiv · Feb 11, 2021Biophysics

Ultrafast pore-loop dynamics in a AAA+ machine point to a Brownian-ratchet mechanism for protein translocation

H. A. Mazal, M. Iljina, I. Riven, G. Haran

The paper measures pore-loop dynamics in ClpB using single-molecule FRET, finding microsecond fluctuations and conformational changes linked to substrate binding and disaggregation activity, suggesting a Brownian-ratchet mechanism.

bioRxiv · Nov 19, 2020Biophysics

Single-molecule spectroscopy reveals dynamic allostery mediated by the substrate-binding domain of a AAA+ machine

M. Iljina, H. Mazal, P. Goloubinoff, I. Riven, G. Haran

This study uses single-molecule FRET to show the NTD of ClpB dynamically interacts with the MD, regulating ATPase and unfolding activity through allosteric signaling.

bioRxiv · Sep 13, 2020Biophysics