Cancer BiologybioRxiv
Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
G. PINTO, I. SAENZ DE SANTA MARIA, P. CHASTAGNER…·C. ZURZOLO
This study shows that glioblastoma stem-like cells form functional tunneling nanotubes (TNTs) that enable mitochondria transfer in 2D and 3D tumor organoids, suggesting a role in therapy resistance.
DOI 10.1042/bcj20200710