Author

I. Stewart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Annis· 1 shared A. Hickey· 1 shared A. J. Hickey· 1 shared A. Schaefer· 1 shared A. Schmalstig· 1 shared B. Jermain· 1 shared B. Miller· 1 shared C. Kim· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Annis

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2 papers

Recent·Most cited

Pharmacokinetic considerations for optimizing inhaled spray-dried pyrazinoic acid formulations

S. B. Yeshwante, P. Hanafin, B. Miller, L. Rank, S. Murcia, C. Xander, A. Annis, V. Baxter, E. Anderson, B. Jermain, R. Konicki, A. Schmalstig, I. Stewart, M. Braunstein, A. Hickey, G. G. Rao

This study develops and evaluates inhaled POA formulations to improve TB treatment by enhancing pulmonary exposure and efficacy against pncA-mutant Mtb.

bioRxiv · Apr 1, 2023Pharmacology & Toxicology

Stable nebulization and muco-trapping properties of Regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19

M. D. McSweeney, I. Stewart, Z. Richardson, H. Kang, Y. Park, C. Kim, K. Tiruthani, W. Wolf, A. Schaefer, P. Kumar, H. Aurora, J. Hutchins, J. M. Cho, A. J. Hickey, S. Y. Lee, S. K. Lai

This paper demonstrates that IN-006, a reformulated Regdanvimab, effectively traps SARS-CoV-2 virus-like particles in human airway mucus and achieves higher lung concentrations in rats when nebulized compared to intravenous delivery.

bioRxiv · Feb 27, 2022Bioengineering