H. Kang

ER-to-lysosome Ca2+ refilling followed by K+ efflux-coupled store-operated Ca2+ entry in inflammasome activation and metabolic inflammation

This study identifies a novel mechanism involving lysosomal Ca2+ release and K+ efflux through KCa3.1 channels in inflammasome activation and metabolic inflammation.

In-situ microscopy-assisted meniscus-guided coating for highly sensitive reduced graphene oxide-based nanocomposite biosensor

The paper develops a meniscus-guided coating technique using in-situ microscopy and CFD modeling to create high-performance rGO-based biosensors with picomolar detection limits.

Blockade of TREM2 ameliorates pulmonary inflammation and fibrosis by modulating sphingolipid metabolism

This study shows that blocking TREM2 reduces pulmonary inflammation and fibrosis by altering sphingolipid metabolism and chemokine expression in macrophages.

Astrocytes are active: An information theoretic approach reveals differences in Ca2+ signaling patterns among distinct astrocyte subtypes

This paper uses an information-theoretic approach to analyze Ca2+ signaling differences among astrocyte subtypes and finds distinct responses to perturbations.

Calcium Sulfate Microparticle Size Modification for Improved Alginate Hydrogel Fabrication and Its Application in 3D Cell Culture

The paper shows that ball-milled calcium sulfate microparticles improve alginate hydrogel fabrication by creating more stable suspensions, leading to homogeneous gels with consistent mechanical properties for 3D cell culture.

Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder Afrotheria

This study analyzes sirenian genomes to identify genomic adaptations to aquatic life and conservation challenges.

Phylogenetic and functional analyses of N6-methyladenosine RNA methylation factors in the wheat scab fungus Fusarium graminearum

This study investigates m6A RNA methylation factors in Fusarium graminearum, identifying copy number variations and functional roles of MTA1 in conidial germination and hyphal branching.

Mechanical Force Imprints Neutrophils to Orchestrate Pulmonary Homeostasis

This study identifies mechanical sensing via Piezo1 as critical for lung-specific neutrophils to maintain pulmonary homeostasis and respond to infection.

Early cellular and molecular signatures correlate with severity of West Nile Virus infection

The paper identifies cellular and molecular signatures associated with varying severities of West Nile Virus infection using multi-omics analysis of immune responses.

Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

This paper shows that MEK1/2 inhibitors reduce MmuPV1 replication and promote tumor regression in mice, suggesting MEK1/2 as a therapeutic target for papillomavirus diseases.

The song does not remain the same: daily singing of adult songbirds prevents passive changes in song structure independently of auditory feedback

This study shows that daily singing in adult zebra finches prevents passive changes in song structure, independent of auditory feedback, and recovery occurs with resumed singing.

Modernizing the original influenza vaccine to enhance protective antibody responses against neuraminidase antigens

This study enhances influenza vaccine efficacy by improving NA antibody responses through modified virions and recombinant NA proteins in a mouse model.

Structural insights into ion conduction by novel cation channel, TMEM87A, in Golgi apparatus

This paper presents a high-resolution cryo-EM structure of TMEM87A, revealing its unique architecture and mechanisms of ion conduction and gating in the Golgi apparatus.

cMYC protein interactions and chromatin association in NUT carcinoma

This study investigates cMYC protein interactions and chromatin association in NUT carcinoma cells, finding that cMYC primarily interacts with the NuA4 KAT5 complex.

Stable nebulization and muco-trapping properties of Regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19

This paper demonstrates that IN-006, a reformulated Regdanvimab, effectively traps SARS-CoV-2 virus-like particles in human airway mucus and achieves higher lung concentrations in rats when nebulized compared to intravenous delivery.

MASiVar: Multisite, Multiscanner, and Multisubject Acquisitions for Studying Variability in Diffusion Weighted Magnetic Resonance Imaging

MASiVar evaluates DWI variability across multiple levels and processing approaches using a multisite, multisubject dataset.

Early flowering in oilseed-type Brassica rapa plants results from nonsense-mediated mRNA decay (NMD) of BrFLC2

The study identifies NMD-mediated degradation of BrFLC2 mRNA as the cause of early flowering in oilseed-type Brassica rapa LP08 plants.

Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

This study generates CCR5-edited T cells and macrophages from nonhuman primate iPSCs, showing resistance to SIV replication.

α1-COP delivers sphingolipid modifiers and controls plasmodesmal callose deposition in Arabidopsis

The paper identifies α1-COP as a negative regulator of callose accumulation by modulating sphingolipid enzyme translocation in Arabidopsis.

Invasive grass dominance over native forbs is linked to shifts in the bacterial rhizosphere microbiome

The paper examines how rhizosphere microbiomes differ between native forbs and invasive grasses and identifies bacterial families linked to competitive outcomes.

CTCF-mediated Genomic Effects of BART Region on Epstein-Barr Virus Chromatin 3D Structure in Gastric Carcinoma Cells

This study investigates how CTCF binding at the BARTp site regulates EBV 3D genome structure and gene expression in EBVaGC cells, showing its role in DNA looping and viral infectivity.

Seminal plasma exosomes evoke calcium signal via CatSper channel to regulate human sperm function

This study shows that seminal plasma exosomes increase human sperm calcium levels via the CatSper channel, improving motility and offering potential clinical applications for asthenozoospermia.

TAZ inhibits GR and coordinates hepatic glucose homeostasis in normal physiologic states

This study identifies TAZ as an inhibitor of GR that regulates hepatic glucose homeostasis by modulating gluconeogenic gene promoter binding.

A common problem in the purification of calicivirus raised by molecular sieving: balance between purification and loss of viral particles

This study evaluates the impact of molecular sieving on Feline Calicivirus stability using cryo-EM and develops a scoring system to assess purification effects.