Genistein enhances NAD+ biosynthesis by binding to Prohibitin 1 and upregulating nicotinamide phosphoribosyltransferase in adipocytes
S. Watanabe, R. Haruyama, K. Umezawa, I. Tomioka, S. Nakamura, S. Katayama, T. Mitani
This study shows genistein increases NAD+ biosynthesis in adipocytes by upregulating NAMPT through PHB1 binding and stabilization of CCAAT/enhancer-binding protein β.
bioRxiv · Apr 20, 2023 · PreprintBiochemistry