T. Mitani

Genistein enhances NAD+ biosynthesis by binding to Prohibitin 1 and upregulating nicotinamide phosphoribosyltransferase in adipocytes

This study shows genistein increases NAD+ biosynthesis in adipocytes by upregulating NAMPT through PHB1 binding and stabilization of CCAAT/enhancer-binding protein β.

Anti-nucleolin aptamer, iSN04, inhibits the inflammatory responses in myoblasts by modulating the β-catenin/NF-κB signaling pathway

This study shows that iSN04, an anti-nucleolin aptamer, reduces inflammation in myoblasts by inhibiting the β-catenin/NF-κB pathway.

The difference in FRET efficiency fluctuation at each end of the actin filament

The paper measures FRET efficiency fluctuations along actin filaments to reveal differences in local flexibility and orientation near each end.