Generation of human iPSC-derived motor neurons with defined regional identities across the rostrocaudal axis
Ken Ning, Ian Tindel, Brijesh Kumar Singh, Benisa Zogu, Ritchie Ho
This study develops three protocols to generate human iPSC-derived motor neurons with defined hindbrain, cervical, and lumbar identities, showing graded rostrocaudal specification and region-specific features.
bioRxiv · Oct 30, 2026 · PreprintNeuroscience