Shaughn Bell

This study compares two protocols for generating human iPSC-derived spinal motor neurons, finding that the extended protocol produces more mature, spinal-specific neurons with enhanced synaptic features.

The paper reports single-cell proteomic maps of human iPSCs and their differentiation into motor neurons, revealing proteomic and transcriptomic discordance.

This study creates a lifespan snRNA-seq atlas of mouse spinal cord, revealing how aging and SOD1-G93A ALS interact regionally and cell-type specifically.

This study develops iPSC-derived prostate organoids with and without BRCA2 mutations, showing tumorigenic changes and cancer markers in mutated organoids.

This study examines transcriptomic changes in grafted human neural progenitor cells and host retinal cells in a retinitis pigmentosa model, identifying mechanisms for vision preservation.