Author

Ibrahim Saleh

Children's Hospital of Philadelphia

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Edward B. LeeiD· 1 shared Elizabeth R. RhoadesiD· 1 shared Hong Xu· 1 shared Manu SharmaiD· 1 shared Neil L. KelleheriD· 1 shared Nima N. NaseriiD· 1 shared Ophir ShalemiD· 1 shared Sapanna ChantarawongiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperNeuroscience

Edward B. LeeORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintAug 9, 2025

Tau Aggregation Results in an Impaired Ability to Counteract Microtubule Destabilization via Specific Combinatorial Tau Phosphorylation Patterns

Nima N. Naseri, Tian Xu, Ibrahim Saleh…·Elizabeth R. Rhoades

This study shows that tau phosphorylation patterns influence microtubule stability, with specific phosphorylations impairing tau's ability to counteract destabilization, suggesting phosphorylation may respond to, rather than precede, MT instability.

DOI 10.1101/2025.08.09.669485

mouseexperimental assay

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