NeurosciencebioRxiv
Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation
Mathias Guayasamin, Lewis R Depaauw-Holt, Ifeoluwa I Adedipe…·Ciaran Murphy‐Royal
This study shows early-life stress causes astrocyte dysfunction in mice, leading to anxiety and fear generalization through impaired synaptic plasticity and neural excitability.
15 citations