Anthony Bosson

Sex-dependent and region-specific morphological adaptations in astrocytes following early-life stress

This study uses sparse eGFP labeling to compare astrocyte morphology across brain regions and sexes in mice, finding sex-dependent and region-specific changes after early-life stress.

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

Astrocyte glucocorticoid receptors mediate sex-specific changes in activity following stress

The paper investigates how stress affects activity levels through interactions between orexin neurons and astrocytes, finding that astrocytic glucocorticoid receptors mediate sex-specific changes in neuronal firing and activity.

Distinct subtypes of astrocytes selectively regulate specific inhibitory synapses

This study identifies two distinct astrocyte subtypes in the hippocampus that selectively regulate inhibitory synapses in specific domains through functional and transcriptional differences.

Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult

This study shows that peripheral inflammation reduces D1-MSN excitability in the NAc by increasing microglial engulfment of glutamatergic inputs.

mTORC1-mediated acquisition of reward-related spatial representations by hippocampal somatostatin interneurons

The paper shows that mTORC1 in hippocampal somatostatin interneurons is essential for learning reward-related spatial representations during a virtual reality task.

Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation

This study shows early-life stress causes astrocyte dysfunction in mice, leading to anxiety and fear generalization through impaired synaptic plasticity and neural excitability.