Author

Ilona M. Vuist

Charles River Laboratories (Netherlands)

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Elizabeth C. M. de LangeiD· 1 shared Mengxu ZhangiD· 1 shared Vivi RottschäferiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperPharmacology & Toxicology

Elizabeth C. M. de LangeORCID

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1 paper

Recent·Most cited

Exploring Kp,uu,BBB Values Smaller than Unity in Remoxipride: A Physiologically-Based CNS Model Approach Highlighting Brain Metabolism in Drugs with Passive Blood-Brain Barrier Transport

Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange

This study investigates the brain distribution of remoxipride, showing that brain metabolism, not just BBB efflux, affects Kp,uu,BBB values less than 1.

European Journal of Pharmaceutical Sciences · Aug 22, 2024Peer-reviewedPharmacology & Toxicology