Author

Vivi Rottschäfer

Leiden UniversityORCID 0000-0002-4150-3486Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Cyriel M. A. PennartziD· 1 shared Daniele AvitabileiD· 1 shared Ed VanBaveliD· 1 shared Elizabeth C. M. de LangeiD· 1 shared Ilona M. Vuist· 1 shared Jiao CheniD· 1 shared Matthijs N. Oude LohuisiD· 1 shared Mengxu ZhangiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperNeuroscience

Cyriel M. A. PennartzORCID

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3 papers

Recent·Most cited

Arterial arcades and collaterals regress under hemodynamics-based diameteradaptation: a computational and mathematical analysis

Vivi Rottschäfer, Willem G.N. Kuppers, Jiao Chen, Ed VanBavel

The paper shows that arterial loops regress under hemodynamics-based diameter adaptation in computational and mathematical models.

Journal of Theoretical Biology · Apr 8, 2025Peer-reviewedPhysiology

The neural and computational architecture of feedback dynamics in mouse cortex during stimulus report

Simone Ciceri, Matthijs N. Oude Lohuis, Vivi Rottschäfer, Cyriel M. A. Pennartz, Daniele Avitabile, Simon van Gaal, Umberto Olcese

The paper analyzes neural activity in mouse cortex during stimulus detection and develops a network model showing PPC mediates report-related activity in V1, with PFC playing a secondary role.

eNeuro · Sep 1, 2024Peer-reviewedNeuroscience

Exploring Kp,uu,BBB Values Smaller than Unity in Remoxipride: A Physiologically-Based CNS Model Approach Highlighting Brain Metabolism in Drugs with Passive Blood-Brain Barrier Transport

Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange

This study investigates the brain distribution of remoxipride, showing that brain metabolism, not just BBB efflux, affects Kp,uu,BBB values less than 1.

European Journal of Pharmaceutical Sciences · Aug 22, 2024Peer-reviewedPharmacology & Toxicology