Targeted Transcriptome Analysis using Synthetic Long Read Sequencing Uncovers Isoform Reprograming in the Progression of Colon Cancer
Silvia Liu, Indira Wu, Yanping Yu, Michael A. Balamotis, Bao‐Guo Ren, Tuval Ben Yehezkel, Jianhua Luo
This study uses LoopSeq, a synthetic long read sequencing method, to analyze isoform changes in colon cancer and identifies novel gene fusions and isoform-specific SNVs.
Communications Biology · Apr 27, 2021Peer-reviewedGenomics