Author

Yanping Yu

University of PittsburghORCID 0000-0002-4140-4074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:long-read sequencing· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2

Frequent Co-Authors

Bao‐Guo Ren· 3 shared Caroline A. Obert· 3 shared Jianhua LuoiD· 3 shared Silvia LiuiD· 3 shared Tuval Ben-Yehezkel· 3 shared Jia-Jun LiuiD· 2 shared Mat Smith· 2 shared Wenjia WangiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Bao‐Guo Ren

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Deep Spatial Sequencing Revealing Differential Immune Responses in Human Hepatocellular Carcinoma

Yanping Yu, Liu Silvia, Caroline A. Obert, Bao-Guo Ren, Marielle Krivet, Kyle Metcalfe, Jia-Jun Liu, Tuval Ben-Yehezkel, Jianhua Luo

This study uses deep spatial sequencing to reveal differential immune responses in HCC and benign liver tissues, showing more intense HCC cell responses to immune cells.

Frontiers in Cell and Developmental Biology · Jun 3, 2025Peer-reviewedCancer Biology

Utility Analyses of AVITI Sequencing Chemistry

Silvia Liu, Caroline A. Obert, Yanping Yu, Junhua Zhao, Bao‐Guo Ren, Jia-Jun Liu, Kelly N. Wiseman, Benjamin J. Krajacich, Wenjia Wang, Kyle S. Metcalfe, Mat Smith, Tuval Ben-Yehezkel, Jianhua Luo

This study compares the AVITI and Illumina sequencing chemistries for DNA and RNA short-read and long-read sequencing, finding AVITI has higher quality scores and lower error rates in short-read applications.

bioRxiv · Apr 18, 2024 · PreprintGenomics

Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells

Silvia Liu, Yanping Yu, Bao‐Guo Ren, Tuval Ben-Yehezkel, Caroline A. Obert, Mat Smith, Wenjia Wang, Alina Ostrowska, Alejandro Soto–Gutiérrez, Jianhua Luo

The paper uses long-read single-cell sequencing to identify mutation-specific mRNA isoforms and fusion transcripts in liver cancer cells, improving classification of cancer versus benign cells.

eLife · Jun 23, 2023Peer-reviewedGenomics

Targeted Transcriptome Analysis using Synthetic Long Read Sequencing Uncovers Isoform Reprograming in the Progression of Colon Cancer

Silvia Liu, Indira Wu, Yanping Yu, Michael A. Balamotis, Bao‐Guo Ren, Tuval Ben Yehezkel, Jianhua Luo

This study uses LoopSeq, a synthetic long read sequencing method, to analyze isoform changes in colon cancer and identifies novel gene fusions and isoform-specific SNVs.

Communications Biology · Apr 27, 2021Peer-reviewedGenomics