Jianhua Luo

This study establishes patient-derived organoids (PDOs) for HNSCC drug response testing, integrating AI-driven histopathology and multi-omics analysis to create a scalable preclinical model.

This study uses deep spatial sequencing to reveal differential immune responses in HCC and benign liver tissues, showing more intense HCC cell responses to immune cells.

IFDlong is a tool for detecting and quantifying isoform and fusion transcripts in long-read RNA-seq data, showing high accuracy and performance in simulations and real datasets.

The paper uses long-read single-cell sequencing to identify mutation-specific mRNA isoforms and fusion transcripts in liver cancer cells, improving classification of cancer versus benign cells.

This study uses LoopSeq, a synthetic long read sequencing method, to analyze isoform changes in colon cancer and identifies novel gene fusions and isoform-specific SNVs.