Io Diakou

Computer-aided drug design and pharmacophore modeling towards the discovery of novel anti-Ebola agents

This study uses computational methods to design novel anti-Ebola agents targeting the virus polymerase.

An updated evolutionary and structural study of TBK1 reveals highly conserved motifs as potential pharmacological targets in neurodegenerative diseases.

This study identifies conserved motifs in TBK1 as potential pharmacological targets for treating Amyotrophic Lateral Sclerosis through evolutionary, structural, and mutational analysis.

Semantic and population analysis of the genetic targets related to COVID-19 and its association with genes and diseases

The paper analyzes genetic targets related to COVID-19 using semantic methods and integrates population data to explore host genetic variation's role in disease.

A genomic study of the Japanese population focusing on the glucocorticoid receptor interactome highlights distinct genetic characteristics associated with stress response

The paper identifies population-specific SNPs in the glucocorticoid receptor interactome in Japanese individuals, highlighting potential roles in stress-related diseases.

ADRA2B and HTR1A: An updated study of the biogenic amine receptors reveals novel conserved motifs which play key role in Mental Disorders.

This study investigates conserved motifs in ADRA2B and HTR1A, two biogenic amine receptors, to understand their role in mental disorders through evolutionary and structural analysis.

DRDs and Brain Derived Neurotrophic Factor share a common therapeutic ground: A novel bioinformatic approach sheds new light towards pharmacological treatment of Cognitive and Behavioral Disorders.

The paper identifies genetic factors associated with cognitive and behavioral disorders using bioinformatics tools and develops regulatory networks for dopamine receptors and BDNF.