Author

Iren Saffarian-Deemyad

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Organism:Arabidopsis· 1 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:plant (other)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Brittney W. ThorntoniD· 1 shared Conner J. LangebergiD· 1 shared David F. SavageiD· 1 shared Erin E. DohertyiD· 1 shared Evan C. DeTurkiD· 1 shared Honglue ShiiD· 1 shared Isabel Esain-GarciaiD· 1 shared Jasmine Amerasekera· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Brittney W. ThorntonORCID

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1 paper

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedAug 1, 2026

✦ In-depth digest

Stepwise DNA unwinding gates TnpB genome-editing activity

Zehan Zhou, Iren Saffarian-Deemyad, Honglue Shi…·Jennifer A. Doudna

Ymu1 TnpB unwinds DNA via a long-lived partially unwound intermediate before a rarely stable open state; the WFR triple variant stabilizes both, boosting plant editing.

1 citation

Arabidopsisplant (other)

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