Author

Irina Dumbravanu

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Caitlin HarrisiD· 1 shared Daniel J. MarstoniD· 1 shared Fabiola VaccaiD· 1 shared Heman Burre· 1 shared Jayani ChristopheriD· 1 shared Mihai L. AzoiteiiD· 1 shared Pranav KannaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Caitlin HarrisORCID

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1 paper

Recent·Most cited

Control of Guanine Exchange Factor Activity Using De Novo Designed Protein Inhibitors

Fabiola Vacca, Daniel J. Marston, Caitlin Harris, Pranav Kannan, Heman Burre, Jayani Christopher, Irina Dumbravanu, Mihai L. Azoitei

This study develops a platform for designing protein inhibitors against Dbl family GEFs, demonstrating their ability to modulate GEF activity in vitro and in cells with high specificity.

bioRxiv · May 28, 2026 · PreprintCell Biology