Jayani Christopher

This study develops a platform for designing protein inhibitors against Dbl family GEFs, demonstrating their ability to modulate GEF activity in vitro and in cells with high specificity.

This paper develops a mammalian surface display platform using the PiggyBac transposon system to screen viral protein variants for improved antigenicity in vaccine design.

The paper designs immunogens that redirect immune responses to a conserved influenza epitope using iterative machine learning and in vivo testing.