BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Engineering Antibody-Drug Conjugates targeting an Adhesion GPCR, CD97
Takamitsu Hattori, Michelle Y. Wang, Alexis D. Corrado…·Shohei Koide
This study develops antibody-drug conjugates targeting CD97, an aGPCR overexpressed in cancer, showing efficacy against AML and GBM cells with minimal off-target toxicity.
3 citations