Author

Isaac Ive

Rice University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:genome assembly· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alice Y. TingiD· 1 shared Boao XiaiD· 1 shared Hailong WangiD· 1 shared Honghao Li· 1 shared Jerzy O. SzablowskiiD· 1 shared Linda Zhixia ShiiD· 1 shared Nicholas A. KalogriopoulosiD· 1 shared Nicolas BuitragoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Alice Y. TingORCID

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2 papers

Recent·Most cited

Cell-Based Sensor for Extracellular DNA

Boao Xia, Nicholas A. Kalogriopoulos, Ruoxin Wen, Zachary M. Lane, Honghao Li, Nicolas Buitrago, Sangsin Lee, Richard Gao, Isaac Ive, Yerim Kim, Alice Y. Ting, Jerzy O. Szablowski

This paper introduces a cell-based sensor called LUNAR that detects extracellular double-stranded DNA with nanomolar sensitivity in mammalian cells.

bioRxiv · Aug 20, 2026 · PreprintSynthetic Biology

53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)

Sameer Bikram Shah, Youhang Li, Shibo Li, Qing Hu, Tong Wu, Yanmeng Shi, Tran Nguyen, Isaac Ive, Linda Zhixia Shi, Hailong Wang, Xiaohua Wu

This study shows that 53BP1 deficiency increases BIR-mediated hyperrecombination, leading to genome instability and potential cancer treatment opportunities.

Nature Communications · Oct 5, 2024Peer-reviewedMolecular Biology