Remote Control of Cell Signaling through Caveolae Mechanics
Satish Kailasam Mani, Nicolas Tardif, Olivier Rossier, Ismail M. Khater, Xuesi Zhou, Victor Breton, Filipe Nunes Vicente, Adiyodi Veettil Radhakrishnan, Céline Gracia, Pamela Gonzalez Troncoso, Isabel Brito, Richard Ruez, Melissa Dewulf, Ghassan Hamarneh, Ivan R. Nabi, , Christophe Lamaze
The paper investigates how mechanical stress affects caveolae mechanics, leading to the release of caveolin-1 scaffolds and modulation of signaling pathways like JAK1, eNOS, PTEN, and PTP1B.
Nature Cell Biology · Jun 1, 2026Peer-reviewedCell Biology