Grégory Giannone

The paper investigates how mechanical stress affects caveolae mechanics, leading to the release of caveolin-1 scaffolds and modulation of signaling pathways like JAK1, eNOS, PTEN, and PTP1B.

This study uses DNA origami probes to investigate nanodomain organization and dynamics in plasma membranes by tracking their movement and interactions with nanodomains.

The paper develops synthetic binders specific to PSD-95 for imaging endogenous proteins with minimal impact on function and compatibility with super-resolution techniques.

This study shows Rac1 activation occurs at the lamellipodium tip, not behind it, and is correlated with membrane protrusion through fast activation-inactivation cycles.