Author

Céline Gracia

Centre National de la Recherche ScientifiqueORCID 0000-0002-3312-6465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Christophe LamazeiD· 2 shared Adiyodi Veettil Radhakrishnan· 1 shared Carlos Ureña MartíniD· 1 shared Cédric M. BlouiniD· 1 shared Christine Viaris de LesegnoiD· 1 shared Cristian SaqueliD· 1 shared Damarys LoewiD· 1 shared Ewan MacDonaldiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Christophe LamazeORCID

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Author profile →

2 papers

Recent·Most cited

Remote Control of Cell Signaling through Caveolae Mechanics

Satish Kailasam Mani, Nicolas Tardif, Olivier Rossier, Ismail M. Khater, Xuesi Zhou, Victor Breton, Filipe Nunes Vicente, Adiyodi Veettil Radhakrishnan, Céline Gracia, Pamela Gonzalez Troncoso, Isabel Brito, Richard Ruez, Melissa Dewulf, Ghassan Hamarneh, Ivan R. Nabi, , Christophe Lamaze

The paper investigates how mechanical stress affects caveolae mechanics, leading to the release of caveolin-1 scaffolds and modulation of signaling pathways like JAK1, eNOS, PTEN, and PTP1B.

Nature Cell Biology · Jun 1, 2026Peer-reviewedCell Biology

Mechanical stress and caveolin-1 control the release of extracellular vesicles with increased tumorigenic properties

Cristian Saquel, Louis Bochler, Ewan MacDonald, Céline Gracia, Christine Viaris de Lesegno, Frederik J. Verweij, Carlos Ureña Martín, Vanessa Masson, Damarys Loew, Graça Raposo, Jacky G. Goetz, Vincent Hyenne, Christophe Lamaze

This study shows mechanical stress increases EV release from cancer cells via caveolin-1, leading to more tumorigenic EVs that promote metastasis.

bioRxiv · Sep 5, 2024 · PreprintCancer Biology