Author

Isabell Lehmkuhl

Düsseldorf University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Afshin Iram· 1 shared Björn StorkiD· 1 shared Constanze WiekiD· 1 shared Doreen Manuela FlossiD· 1 shared Helmut HanenbergiD· 1 shared Jasmin Thuy Vy Nguyen· 1 shared Julia HesseiD· 1 shared Jürgen SchelleriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Afshin Iram

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1 paper

Recent·Most cited

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, Mohammad Reza Ahmadian, Björn Stork, Doreen Manuela Floss, Roland P. Piekorz

This study shows SIRT4 promotes autophagy by modulating ULK1 phosphorylation, independent of HDAC6 and OPA1, and identifies its role in early autophagy initiation.

FEBS Open Bio · Nov 20, 2025Peer-reviewedBiochemistry