Author

Constanze Wiek

Düsseldorf University HospitalORCID 0000-0003-2214-8148Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Afshin Iram· 1 shared Björn StorkiD· 1 shared Doreen Manuela FlossiD· 1 shared Helmut HanenbergiD· 1 shared Isabell Lehmkuhl· 1 shared Jasmin Thuy Vy Nguyen· 1 shared Julia HesseiD· 1 shared Jürgen SchelleriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Afshin Iram

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1 paper

Recent·Most cited

BiochemistryFEBS Open BioPeer-reviewedNov 20, 2025

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel…·Roland P. Piekorz

This study shows SIRT4 promotes autophagy by modulating ULK1 phosphorylation, independent of HDAC6 and OPA1, and identifies its role in early autophagy initiation.

DOI 10.1002/2211-5463.70164

humanproteomics

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