Distinct atypical chemokine receptor 1 determinants underlie bacterial toxins recognition and pore formation
Aurélien Fouillen, Elodie Logerot, Zainab Ammar, Tristan Girbau, Isabelle Brabet, Omolade Otun, Rym Ben Boubaker, Camille Le Drezen, Maria Bacia‐Verloop, Ambroise Desfosses, Cédric Leyrat, Sébastien Granier, Chérine Bechara
This study identifies distinct determinants of ACKR1 recognition by bacterial toxins, revealing a two-step mechanism involving sulfotyrosine binding and extracellular vestibule interaction.
bioRxiv · Sep 10, 2026 · PreprintBiochemistry