Tau controls NMDA receptor trafficking during homeostatic synaptic plasticity
Xuan Ling Hilary Yong, Kristie Stefanoska, William Chin Kwan, Isabelle Irons, Pranesh Padmanabhan, Evgeniia Samokhina, Andrew Kneynsberg, Nathalie Dehorter, Arne Ittner, Jürgen Götz, Victor Anggono
This study identifies Tau as a regulator of NMDA receptor trafficking during homeostatic synaptic plasticity, showing that Tau phosphorylation and interactions with Fyn kinase modulate receptor stability.
bioRxiv · Jul 28, 2025 · PreprintNeuroscience