Nathalie Dehorter

This study shows that reduced dorsal CA1 activity in Cntnap2 knockout mice impairs temporal memory retention and flexible spatial memory, linking hippocampal dysfunction to cognitive inflexibility in autism.

This study identifies sex-specific differences in serotonergic circuit connectivity and gene expression in the dorsal raphe nucleus, linking these differences to sex-dependent anxiety-like behaviors.

This paper develops a hydrogel-based system to reprogram astrocytes into neurons by delivering reprogramming factors and valproic acid, enhancing neural repair.

This study identifies Vaultrc5 as a noncoding RNA that regulates synaptic vault trafficking and RNA cargo dynamics, impacting learning and memory.

This study identifies Tau as a regulator of NMDA receptor trafficking during homeostatic synaptic plasticity, showing that Tau phosphorylation and interactions with Fyn kinase modulate receptor stability.

This study identifies NTT4/SLC6A17 as a presynaptic glutamine transporter essential for glutamate supply and neurotransmission, with behavioral implications.

This study shows that autoimmune response to alpha-synuclein antigen causes Parkinson's disease-like symptoms in mice through immune cell infiltration and inflammation.

CHEUI predicts m6A and m5C modifications at single-molecule resolution, revealing co-occurrence of these modifications in mRNAs across cell lines and tissues.

This study shows that loss of the Er81 transcription factor in cholinergic interneurons alters their electrophysiological properties and impairs habit formation in adult mice.

This study shows that stress-induced PTSD-like memory worsens ASD traits in mice through hyperactivation of the prefrontal cortex and parvalbumin interneuron dysfunction, and suggests recontextualization as a potential treatment.