Cryo-EM structure of the transcription termination factor Rho from Mycobacterium tuberculosis reveals mechanism of resistance to bicyclomycin
Emmanuel Saridakis, Rishi Kishore Vishwakarma, Joséphine Lai‐Kee‐Him, Kevin Martin, Isabelle Simon, Martin Cohen‐Gonsaud, Franck Coste, Patrick Bron, Emmanuel Margeat, Marc Boudvillain
The paper determines the cryo-EM structure of M. tuberculosis Rho, explaining its resistance to bicyclomycin and low enzymatic activity.
Communications Biology · Feb 9, 2022Peer-reviewedMolecular Biology