Emmanuel Margeat

The paper investigates the spatial organization of Rho and RNA Polymerase in Salmonella cells, revealing distinct localization patterns and functional differences between Rho variants.

This paper introduces a triple-labeling strategy for single molecule FRET to study conformational changes in GPCRs, revealing a previously unknown intermediate state.

The paper investigates how single-stranded DNA facilitates sigma subunit loading onto RNA polymerase, enabling the formation of the open promoter complex in Mycobacterium tuberculosis.

This study shows that the conformational changes of the bacterial ABC transporter BmrA are influenced by membrane curvature, affecting its activity and conformational states.

The paper determines the cryo-EM structure of M. tuberculosis Rho, explaining its resistance to bicyclomycin and low enzymatic activity.