Rishi Kishore Vishwakarma

This study isolates and structures native Pol II transcription complexes and nucleosomes from Drosophila embryos, revealing new insights into transcription dynamics and nucleosome interactions.

The paper investigates transcription termination in cyanobacteria, finding that most transcription units lack canonical intrinsic terminators and suggesting novel termination mechanisms.

The paper investigates how single-stranded DNA facilitates sigma subunit loading onto RNA polymerase, enabling the formation of the open promoter complex in Mycobacterium tuberculosis.

This study presents the structure of Si3, a unique insertion in cyanobacterial RNA polymerase, and shows it does not affect catalytic activity despite large motion.

This paper reveals the structural mechanism of NusG-dependent transcription pausing by showing how NusG interacts with the TTNTTT motif to inhibit RNAP conformational changes required for RNA synthesis.

This study reveals how the {sigma}B factor induces RNAP oligomerization into a supramolecular complex, leading to auto-inhibition of transcription initiation in Mycobacterium tuberculosis.

The paper determines the cryo-EM structure of M. tuberculosis Rho, explaining its resistance to bicyclomycin and low enzymatic activity.