Genetic risk implicating endolysosomal network genes correlates with endolysosomal dysfunction across neural cell types in Alzheimer's disease
Shannon E. Rose, Katherine E. Prater, Sainath Mamde, Isabelle Smith, Yu Fan Lin, Alexandra Cochoit, Aquene N. Reid, Corbin S.C. Johnson, Wei Qiu, Samuel D. Strohbehn, Catilin S. Latimer, C. Dirk Keene, Su‐In Lee, Kevin Z. Lin, Bradley A. Rolf, , Suman Jayadev
This study shows that genetic risk variants in endolysosomal network genes correlate with endolysosomal dysfunction in neural cells in Alzheimer's disease.
bioRxiv · Mar 16, 2025 · PreprintNeuroscience