Author

Ivan Zadra

Universitat Pompeu FabraPrimary ORCID profile (0000-0002-4055-3238 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Ivan ZadraiD1 paper · Universitat Pompeu Fabra

Biology Disciplines

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ana JaniciD· 1 shared Anna Benito· 1 shared Carlos Manuel MartíneziD· 1 shared Davor Orsolic· 1 shared Dimitri Kounis· 1 shared Elisabetta MereuiD· 1 shared Etna AbadiD· 1 shared Fran Supek· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ana JanicORCID

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1 paper

Recent·Most cited

Dual inhibition of the nonsense mediated mRNA decay enhances tumour immunogenicity, drives immunoediting, and potentiates checkpoint blockade

Ivan Zadra, Davor Orsolic, Dimitri Kounis, Mario Acera Mateos, Guillermo Palou Márquez, Etna Abad, Laura Ortet, Anna Benito, Yacine Kharraz, Carlos Manuel Martínez, Elisabetta Mereu, Fran Supek, Ana Janic

This study shows that inhibiting nonsense-mediated mRNA decay enhances tumour immunogenicity, drives immunoediting, and improves checkpoint blockade efficacy in preclinical models.

bioRxiv · Dec 8, 2025 · PreprintCancer Biology