Author

J. A. Agren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. G. Clark· 2 shared M. Munasinghe· 2 shared D. Finkelshtein· 1 shared D. S. Tadele· 1 shared J. G. Scott· 1 shared J. Kesseli· 1 shared M. A. Schenkel· 1 shared M. M. Patten· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersEvolutionary Biology

A. G. Clark

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Author profile →

4 papers

Recent·Most cited

Quantifying internal conflicts and their threats to organismal form and fitness

M. A. Schenkel, M. M. Patten, J. A. Agren

The paper introduces metrics to quantify internal conflicts within organisms and applies them to genomic imprinting and sex ratio distortion.

bioRxiv · Feb 5, 2024Evolutionary Biology

Spatial cumulant models enable spatially informed treatment strategies and analysis of local interactions in cancer systems

S. Hamis, P. Somervuo, J. A. Agren, D. S. Tadele, J. Kesseli, J. G. Scott, M. Nykter, P. Gerlee, D. Finkelshtein, O. Ovaskainen

This paper introduces spatial cumulant models to analyze and improve treatment strategies for cancer cell populations modeled as spatio-temporal point processes.

bioRxiv · May 7, 2022Cancer Biology

Mitochondrial-Y chromosome epistasis in Drosophila melanogaster

J. A. Agren, M. Munasinghe, A. G. Clark

This study examines mitochondrial-Y chromosome epistasis in Drosophila melanogaster by analyzing longevity and gene expression across isogenic strains with different mitochondrial and Y chromosome origins.

bioRxiv · Oct 17, 2019Evolutionary Biology

Sexual Conflict through Mother’s Curse and Father’s Curse

J. A. Agren, M. Munasinghe, A. G. Clark

This study examines how genetic transmission asymmetries cause and resolve sexual conflicts through Mothers Curse and Fathers Curse mechanisms using analytical models and simulations.

bioRxiv · Jun 12, 2018Evolutionary Biology