Author

J. A. Altin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Organism:non-human primate· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

J. T. Ladner· 3 shared A. S. Boyle· 2 shared A. L. Engelbrektson· 1 shared A. Pina· 1 shared A. Schuettenberg· 1 shared D. E. Kainov· 1 shared E. A. Elko· 1 shared E. J. Kelley· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

J. T. Ladner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Recurrent SARS-CoV-2 mutations at Spike D796 evade antibodies from pre-Omicron convalescent and vaccinated subjects

E. A. Elko, H. Mead, G. A. Nelson, J. Zaia, J. T. Ladner, J. A. Altin

The paper shows that SARS-CoV-2 mutations at Spike D796 (D796Y and D796H) evade antibodies from pre-Omicron convalescent and vaccinated individuals.

Microbiology Spectrum · Feb 6, 2024Peer-reviewedImmunology

Highly-multiplexed serology for non-human mammals

A. Schuettenberg, A. Pina, M. Metrailer, R. G. Pelaez-Sanchez, P. Agudelo-Florez, J. Alvaro Lopez, L. Ryle, F. P. Monroy, J. A. Altin, J. T. Ladner

This paper demonstrates the use of highly-multiplexed serology in non-human mammals using commercial reagents and describes a competitive FLISA assay for selecting optimal capture proteins.

bioRxiv · May 24, 2022Immunology

A framework to identify antigen-expanded T Cell Receptor (TCR) clusters within complex repertoires

V. Ceglia, E. J. Kelley, A. S. Boyle, Y. Levy, G. Zurawski, J. A. Altin

This paper introduces a framework to identify antigen-specific TCR clusters in complex repertoires using deep sequencing and antigen-driven expansion, enabling personalized antigen assignment without cell isolation.

bioRxiv · May 21, 2021Immunology

Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with an endemic human CoV

J. T. Ladner, S. N. Henson, A. S. Boyle, A. L. Engelbrektson, Z. W. Fink, F. Rahee, J. D'ambrozio, K. E. Schaecher, M. Stone, W. Dong, S. Dadwal, J. Yu, M. A. Caligiuri, P. Cieplak, M. Bjoras, , J. A. Altin

This study uses PepSeq to map SARS-CoV-2 antibody epitopes and identifies cross-reactivity with hCoV-OC43.

bioRxiv · Jul 27, 2020Immunology