The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis
J. A. Alvarez, E. Gas-Pascual, S. Malhi, F. N. Njume, J. C. Sanchez-Arcila, H. van der Wel, Y. Zhao, G. Ceron, J. Posada, S. P. Souza, G. S. Yap, C. West, K. D. C. Jensen
This paper identifies and characterizes glycosyltransferases in Toxoplasma gondii that modify GPI sidechains, showing that their absence increases parasite virulence.
bioRxiv · Feb 21, 2024 · PreprintMicrobiology