Author

E. Gas-Pascual

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. M. West· 3 shared C. G. Baptista· 2 shared H. van der Wel· 2 shared A. Dittmar· 1 shared A. Lis· 1 shared B. Deng· 1 shared C. West· 1 shared D. Thieker· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

C. M. West

Mutual co-authors in cluster

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4 papers

Recent·Most cited

The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis

J. A. Alvarez, E. Gas-Pascual, S. Malhi, F. N. Njume, J. C. Sanchez-Arcila, H. van der Wel, Y. Zhao, G. Ceron, J. Posada, S. P. Souza, G. S. Yap, C. West, K. D. C. Jensen

This paper identifies and characterizes glycosyltransferases in Toxoplasma gondii that modify GPI sidechains, showing that their absence increases parasite virulence.

bioRxiv · Feb 21, 2024 · PreprintMicrobiology

Toxoplasma gondii F-Box Protein L2 Silences Feline-Restricted Genes Necessary for Sexual Commitment

C. G. Baptista, S. Hosking, E. Gas-Pascual, L. Ciampossine, S. Abel, M.-A. Hakimi, V. Jeffers, K. G. Le Roch, C. M. West, I. Blader

This paper identifies TgFBXL2, an F-box protein in Toxoplasma gondii, which represses feline-restricted genes required for sexual commitment by modulating SCF-E3 ubiquitin ligase activity.

bioRxiv · Dec 18, 2023 · PreprintMicrobiology

A glycogenin homolog controls Toxoplasma gondii growth via glycosylation of an E3 ubiquitin ligase

M. Mandalasi, H. W. Kim, D. Thieker, M. O. Sheikh, E. Gas-Pascual, K. Rahman, P. Zhao, N. G. Daniel, H. van der Wel, T. H. Ichikawa, J. N. Glushka, L. Wells, R. J. Woods, Z. A. Wood, C. M. West

This study identifies Gat1, a glycogenin homolog, as essential for adding the terminal sugar to Skp1 in Toxoplasma gondii, which is critical for parasite growth.

bioRxiv · Feb 2, 2020 · PreprintMicrobiology

Toxoplasma F-Box Protein 1 is Required for Daughter Cell Scaffold Function During Parasite Replication

C. G. Baptista, A. Lis, B. Deng, E. Gas-Pascual, A. Dittmar, W. Sigurdson, C. M. West, I. J. Blader

This paper identifies TgFBXO1 as an F-box protein essential for daughter cell scaffold function in Toxoplasma gondii, demonstrating its role in parasite replication.

bioRxiv · Jun 14, 2019Microbiology