Author

J. A. Bertrand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

D. Overby· 2 shared A. Garcia Jimenez· 1 shared A. Marcionetti· 1 shared A. Spenlehauer· 1 shared C. N. Rudzitis· 1 shared C. Riginos· 1 shared C. Silvestri· 1 shared D. F. Woodward· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

D. Overby

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Author profile →

3 papers

Recent·Most cited

Gene flow throughout the evolutionary history of a polymorphic and generalist clownfish

S. Schmid, M. Bachmann Salvy, A. Garcia Jimenez, J. A. Bertrand, F. Cortesi, S. Heim, F. Huyghe, G. Litsios, A. Marcionetti, J. O'Donnell, C. Riginos, V. Tettamanti, N. Salamin

This study uses whole-genome data to show A. clarkii has a single species status with pervasive gene flow and color polymorphism not linked to population structure.

bioRxiv · Oct 19, 2023 · PreprintEvolutionary Biology

TRPM4 is required for calcium oscillations downstream from the stretch-activated TRPV4 channel

O. Yarishkin, T. T. Phuong, F. Vazquez-Chona, J. A. Bertrand, S. Redmon, M. Lakk, J. M. Baumann`, C. N. Rudzitis, E. M. Hwang, D. Overby, D. Krizaj

The paper shows TRPM4 is required for calcium oscillations downstream from TRPV4 in trabecular meshwork cells, linking mechanical stretch to intracellular signaling.

bioRxiv · Dec 15, 2021 · PreprintCell Biology

Gene Deletion Studies Reveal A Critical Role For Prostamide/Prostaglandin F2α Synthase In Prostamide F2α Formation

J. A. Bertrand, D. F. Woodward, J. M. Sherwood, A. Spenlehauer, C. Silvestri, F. Piscitelli, V. Di Marzo, M. Yamazaki, K. Sakimura, K. Watanabe, D. Overby

This study deletes the PM/PGFS gene in mice and finds elevated intraocular pressure, suggesting PM/PGFS regulates prostanoid levels that affect eye pressure.

bioRxiv · Apr 1, 2020 · PreprintPharmacology & Toxicology