PI3Kγ pathway contributes to neuroinflammation and neuronal death induced by Zika virus infection
Danielle Cunha Teixeira, Gabriel Henrique Campolina-Silva, Fernanda Martins Marim, Felipe Rocha da Silva Santos, Celso Martins Queiroz‐Junior, Pedro Augusto Carvalho Costa, Fernanda L. Tana, Luiz Pedro Souza‐Costa, Jordane Clarisse Pimenta, J. A. Carvalho, Vinícius Amorim Beltrami, Felipe Emanuel Oliveira Rocha, Drielle Viana Vieira, Evandro Gonçalves Dornelas, Giovana Cougo Ferreira, , Vivian Vasconcelos Costa
This study investigates the role of the PI3Kγ pathway in ZIKV-induced neuroinflammation and neuronal death, finding that its inhibition reduces viral replication and neuroinflammatory responses.
Immunology · Feb 7, 2026Peer-reviewedImmunology