Aline Silva de Miranda

This study investigates the role of the PI3Kγ pathway in ZIKV-induced neuroinflammation and neuronal death, finding that its inhibition reduces viral replication and neuroinflammatory responses.

This study identifies MrgD's role in modulating neurotransmission in the nigrostriatal pathway through proteomic analyses and behavioral assays, revealing impaired synaptic exocytosis and altered behavior in MrgD-deficient mice.

This study establishes a sex-dependent mouse model of post-COVID syndrome, showing neuropsychiatric and musculoskeletal complications in females that are prevented by ovariectomy.

This study identifies neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model, showing early cognitive deficits and brain atrophy linked to prion-like spread of misfolded alpha-synuclein.