β-lactamase expression induces collateral sensitivity in Escherichia coli
C. Herencias, L. Alvaro-Llorente, P. Ramiro-Martinez, A. Munoz-Cazalla, J. DeLaFuente, J. A. Castillo-Polo, R. Canton, A. San Millan, J. Rodriguez-Beltran
This study shows that β-lactamase expression in E. coli induces collateral sensitivity to colistin and azithromycin, suggesting a therapeutic strategy to counter mobile AMR.
bioRxiv · Nov 22, 2023 · PreprintMicrobiology