Author

J. A. Hollywood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Organism:rat· 1

Frequent Co-Authors

A. J. Davidson· 2 shared A. Chatterjee· 1 shared A. Przepiorski· 1 shared B. G. Matthews· 1 shared E. J. Buckels· 1 shared E. J. Wolvetang· 1 shared P. K. Kallingappa· 1 shared P. M. Lewis· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

A. J. Davidson

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2 papers

Recent·Most cited

Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

J. A. Hollywood, P. K. Kallingappa, P. Y. Cheung, R. M. Martis, S. Sreebhavan, A. Chatterjee, E. J. Buckels, B. G. Matthews, P. M. Lewis, A. J. Davidson

This paper develops a new cystinosis rat model using CRISPR/Cas9 to recapitulate the disease phenotype and progression more accurately than existing models.

bioRxiv · Jun 29, 2021Physiology

Use of human iPSCs and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy to treat cystinosis

J. A. Hollywood, A. Przepiorski, P. T. Harrison, E. J. Wolvetang, A. J. Davidson, T. M. Holm

This study uses human iPSCs and kidney organoids to show that combining cysteamine and mTOR inhibition improves cystinosis treatment by correcting multiple disease phenotypes.

bioRxiv · Apr 1, 2019Pathology