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2 papers
Recent·Most cited
K. Kamstra, M. Rizwan, J. A. Horsfield, D. Pretz, P. R. Shepherd, D. R. Grattan, A. Tups
This study shows leptin regulates glucose homeostasis through the canonical Wnt pathway in zebrafish and mice.
bioRxiv · Feb 16, 2021 · PreprintPhysiology
C. V. Chin, J. Antony, S. Ketharnathan, G. Gimenez, K. M. Parsons, J. He, A. J. George, A. Braithwaite, P. Guilford, R. D. Hannan, J. A. Horsfield
The paper identifies GSK3 inhibitors as synthetic lethal with cohesin mutations, revealing Wnt pathway activation as a therapeutic target in cohesin mutant cancers.
bioRxiv · Jul 23, 2020Cancer Biology