Author

P. R. Shepherd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Tups· 1 shared B. Sorrenson· 1 shared D. Pretz· 1 shared D. R. Grattan· 1 shared G. Laible· 1 shared J. A. Horsfield· 1 shared J. K. Oh· 1 shared K. B. Tran· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Tups

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Glucose regulates expression of pro-inflammatory genes IL-1β and IL-12 through a mechanism involving hexosamine biosynthesis pathway dependent regulation of α-E catenin in the RAW 264.7 macrophage cell line

W. C. Dissanayake, J. K. Oh, B. Sorrenson, P. R. Shepherd

This study shows high glucose increases IL-1β and IL-12 expression in macrophages via hexosamine biosynthesis pathway-dependent regulation of α-E catenin.

bioRxiv · Apr 14, 2021Cell Biology

Leptin regulates glucose homeostasis via the canonical WNT pathway.

K. Kamstra, M. Rizwan, J. A. Horsfield, D. Pretz, P. R. Shepherd, D. R. Grattan, A. Tups

This study shows leptin regulates glucose homeostasis through the canonical Wnt pathway in zebrafish and mice.

bioRxiv · Feb 16, 2021 · PreprintPhysiology

Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in model systems of cancer.

Q. Wang, W. Gavin, N. Masiello, K. B. Tran, G. Laible, P. R. Shepherd

This paper shows that cetuximab produced in a genetically engineered goat mammary gland is as effective as the commercial version in cancer models.

bioRxiv · Jun 4, 2020Bioengineering