Polymer-mediated oligonucleotide delivery enables construction of barcoded 3D cultures for spatial single-cell analysis
J. J. King, A. Mowla, J. A. Kretzmann, M. Norret, U. D. Kadolsky, M. Iqbal, A. Saxena, S. S. A. Mamsa, S. E. Amos, Y. S. Choi, B. F. Kennedy, K. S. Iyer, N. M. Smith, C. W. Evans
The paper introduces a method to create barcoded 3D cell cultures for spatial single-cell analysis using polymer-mediated oligonucleotide delivery and multiplex single-cell RNA sequencing.
bioRxiv · Nov 20, 2023 · PreprintBioengineering